Most recently, he served as President and Chief Executive Officer of Advaxis Inc., Mr. O’Connor successfully turned around the company, raising more than $300 million in funding and licensing deals, transforming it into a patient-focused, leading cancer immunotherapy company. He was also instrumental in establishing major partnerships with companies that include Amgen Inc., Merck & Co. and Bristol Myers Squibb. In addition, under his leadership, the company advanced four new cancer immunotherapy drug candidates into clinical trials, as well as several PD-1 combination clinical studies with Keytruda®* and Opdivo®*. Previously, Mr. O’Connor was Senior Vice President for ImClone Systems where he supported the clinical development, launch, and commercialization of ERBITUX®*, and the sale of the company to Eli Lilly in 2008. Mr. O’Connor served as General Counsel at PharmaNet (inventive Health) and was part of the senior leadership team that grew the company from a start-up contract research organization into a leader in clinical research.
Mr. O’Connor is a 1995 graduate of the Penn State University’s Dickinson School of Law in Carlisle, Pennsylvania and currently serves as an Entrepreneur Trusted Advisor to its Dean. He graduated from the United States Marines Corps Officer Candidate School in 1988 and was commissioned as an officer in the U.S. Marines, attaining the rank of Captain while serving in Saudi Arabia during Operation Desert Shield. Mr. O’Connor is currently the Vice Chairman of BioNJ and was a former New Jersey criminal prosecutor.
Dr. Twitty brings over 20 years of experience in tumor immunology and cancer immunotherapy, including the discovery and development of OncoSec’s leading clinical immune monitoring and biomarker program.
Dr. Twitty earned his PhD from Oregon Health & Science University where his work was focused on novel tumor vaccine strategies and was awarded an American Cancer Society fellowship training grant for his post-doctoral studies in Dr. Bernard Fox’s Molecular Tumor Immunology Laboratory. After developing a pre-clinical and clinical immunological program focused on glioblastoma at Tocagen, Dr. Twitty joined Oncosec. Previously, Dr. Twitty held scientific positions of increasing responsibility at Bayer Pharmaceuticals and Cell Genesys, Inc.
Ms. Bonstein has extensive experience in leading biotech companies. Prior to joining OncoSec, Sara served as the Chief Financial Officer, Secretary, Treasurer and Executive Vice President at Advaxis, Inc., where she raised approximately $300 million in the capital marketplace and licensing deals. She established strong financial controls and streamlined business operations, was responsible for the overall leadership and management of its operations, including corporate finance, investor relations, business development, IT, facilities, legal and human resources. While at Eli Lilly & Company, Sara was a Six Sigma Champion and Black Belt. Prior to her Six Sigma role, Sara was the Director of Finance where she led all budget and forecast activities for preclinical, clinical and manufacturing research and development. Prior to joining ImClone, Sara was a financial analyst at Johnson & Johnson.
Ms. Bonstein earned a bachelor’s of science degree in finance with a minor in economics from The College of New Jersey and a M.B.A. from Rider University.
Prior to joining OncoSec Kellie served as Executive Vice President and General Manager, Clinical Solutions at Syneos Health. As a member of the Syneos Health Clinical executive leadership team, Ms. Malloy Foerter was responsible for the development and growth of multiple portfolios across therapeutic areas which included a strong focus on oncology and hematology trials, for the world’s leading biopharmaceutical companies. Earlier, Ms. Malloy Foerter spent 20 years at inVentiv Health (previously PharmaNet) where she held multiple positions of increasing responsibility, most recently serving as Senior Vice President, Clinical Research. Prior to inVentiv, she served as Senior Project Associate, Clinical Research Associate and Clinical Studies Assistant at Covance.
Ms. Malloy Foerter has a Bachelor of Science degree from Saint Joseph’s University in Philadelphia, PA.
Mr. Loiacono draws on his extensive business, science and legal experience to head corporate development at OncoSec. Prior to joining OncoSec, Mr. Loiacono was the head of legal at Advaxis Inc., where he successfully negotiated and closed four strategic licensing transactions totaling approximately $75 million. Prior to Advaxis Keir spent 7 years in private practice as a licensed patent attorney with the Lerner David law firm. At Lerner David he specialized in transactions, as well as the monetization and management of IP portfolios for medical device and life science clients, including Fortune 500 companies, and successfully completed numerous transactions. Prior to practicing law, Keir was part of a launching sales force at OraPharma, Inc., which was later acquired by Johnson & Johnson, where he held positions of increasing responsibility in the commercial organization.
Mr. Loiacono hold a bachelor’s degree in biology (Cum laude) from Manhattan College and a Juris Doctorate from the Elisabeth Haub School of Law.
With more than 35 years of experience in the pharmaceutical industry, Dr. Ashworth is well-versed in drug development and global regulatory strategies and has made significant contributions to the FDA approval of 12 new drugs.
Prior to joining OncoSec, Dr. Ashworth served as Vice President, Regulatory Affairs, Quality & Compliance for Advaxis, Inc., where he developed and executed the global regulatory strategy for the company’s immunotherapy platform and served as the company’s regulatory representative for clinical development programs involving Amgen, Bristol-Myers Squibb and Merck. Importantly, Dr. Ashworth was instrumental in securing a groundbreaking investigational new drug application (IND) for a personalized medicine, neo-epitope program. Before Advaxis, Dr. Ashworth was Vice-President, Global Regulatory Affairs at NPS Pharmaceuticals, Inc., where he built the company’s international regulatory department and was instrumental in negotiating the approval of NATPARA (PTH) for hypoparathyroidism. As Vice-President, Global Regulatory Affairs for Otsuka Pharmaceutical Development, Inc., Dr. Ashworth was responsible for the regulatory strategy for the company’s flagship product, ABILIFY®*. Dr. Ashworth’s career experience also includes regulatory positions at Biovail Corporation, Forest Laboratories, Inc., Knoll Pharmaceutical Company (BASF), and CIBA-Geigy Corporation.
Dr. Ashworth earned a B.S. in Chemistry from St. John’s University and his Ph.D. in Organic Chemistry from MIT.
Prior to joining OncoSec, Mr. Rodriguez served as Senior Director of Product Development for Cytori Therapeutics, where he was responsible for the development of Cytori’s stem and regenerative cell products. Mr. Rodriguez biomedical product manufacturing experience includes both domestic and OUS manufacturing with specific experience in Europe, South America and Asia.
Mr. Rodriguez has held positions of increasing responsibility in the biomedical and product development fields since beginning his career at Johnson & Johnson Medical Inc in 1987. In addition to Mr. Rodriguez relevant immunotherapy and oncology experience with electroporation product at both Inovio Biomedical and Genetronics, Mr. Rodriguez tenure includes development of product with Advanced Sterilization Products, Gynecare, Ethicon Endo-Surgery and Ethicon Inc.
Mr. Rodriguez has a bachelor’s degree in Manufacturing Engineering from National University, and a degree in Executive Perspective for Scientists and Engineers from the University of California, San Diego.