Supports R&D team efforts on preclinical projects with an emphasis on validating novel immune-oncology therapeutic candidates. The successful candidate will conduct bench experiments for various projects under the guidance of R&D scientists.
Essential Job Duties/Responsibilities:
Interacts with supervising scientists daily to understand the goals of projects and their experimental needs to coordinate logistics of research studies in R&D.
Execute in vitro and in vivo experiments to evaluate the preclinical efficacy and mechanism of novel immune-therapeutic approaches.
Assist with the collection of murine tissue samples and the processing of those samples.
Perform flow cytometry based analysis of tumor cells and immune cells.
Perform in vitro assays (cell culture, ELISA, PCR, Western Blot).
Maintain clear and up-to-date laboratory notebook and records of research objectives, methods, and results.
Prepare and present key research findings at R&D group meetings regularly as needed.
Bachelor’s degree in a relevant biological discipline.
Demonstrated interest and experience in immunology, cancer biology, molecular biology.
1-3 years of relevant laboratory experience in academic or industry research setting in the following areas:
Cell culture experience required, with tissue culture experience preferred.
Animal (mice) model tissue sample collection and sample analysis experience preferred.
In vivo tumor regression study experience is highly desirable.
Tissue extraction from animal models and ex vivo experiments is preferred.
Multi-parameter flow cytometry and proficiency in FACS data analysis are desirable.
Must possess following attributes:
Working knowledge of key experimental techniques (cell culture, basic FACS, ELISA, PCR, Western Blot).
Ability to manage time and multiple experiments in a fast-paced industry laboratory.
Able to accept directions from scientists to set weekly experimental goals.
Clear communication skills to receive directions and discuss project plans with assigned supervisors to ensure alignment of tasks with R&D goals.
Strong attention to detail with excellent record-keeping and reporting skills.
Adept at common software suites (e.g. Microsoft Office)
Learn to use professional concepts, applies company policies and procedures to resolve routine issues. Works on scientific problems of limited scope following standard practices and procedures to analyze situations or research data. Normally receives regular and detailed instructions at work for all assigned projects.
While performing the duties of this job, the employee is regularly required to stand; walk; sit; use hands to finger, handle, or feel; reach with hands and arms; climb or balance; stoop, kneel, crouch, see, talk or hear in a standard office environment. In a lab setting, occasionally use hands to finger, handle objects, tools, or controls. Employee must occasionally lift and/or move up to 20 pounds.