Technology

Publications

The following posters and presentations regarding OncoSec’s technology and clinical data have been presented at several scientific conferences and meetings

 

Clinical and biomarker analyses of a phase II study of intratumoral tavokinogene telseplasmid (pIL-12) plus pembrolizumab in stage III/IV melanoma patients predicted to not respond to anti-PD-1SITC 2017

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Intratumoral Administration Of A Multigene Construct By Electroporation Can Effectively Modulate Anti-Tumor Response In A Murine B16.f10 Model

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Clinical Immune Monitoring and Biomarker Data of Tavo Monotherapy Compared to Tavo with Pembrolizumab in Metastatic Melanoma Supports the Rationale for Combination Therapy

9th Annual World Congress of Melanoma – A Joint Meeting with the Society of Melanoma Research

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Intratumoral Delivery of a P2A-linked Bicistronic IL-12 Construct Leads to High Intratumoral Expression and Systemic Anti-tumor Response

American Association of Cancer Research (AACR) Annual Meeting 2017

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Intratumoral Electroporation-Mediated IL-12 Gene Therapy can Enhance Tumor Immunogenicity

Keystone Symposia Conference “Cancer Immunology and Immunotherapy: Taking a Place in Mainstream Oncology” 2017

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Immune Monitoring Outcomes of Patients with Stage III/IV Melanoma Treated with a Combination of Pembrolizumab and Intratumoral Plasmid Interleukin 12 (pIL-12)

ASCO-SITC 2017

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Phase II Study of Intratumoral Plasmid Interleukin 12 (pIL-12) with Electroporation

SITC 2016

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Intratumoral IL-12 Therapy in HNSCC

EUROGIN 2016

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A Novel Applicator for Endoscopic Gene Electro-Transfer
AACR Engineering and Physical Sciences in Oncology

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Feedback Optimized Gene Electro-Transfer for Immunotherapy

AACR Engineering and Physical Sciences in Oncology

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Priming response to anti-PD1/PDL1 blockade with intratumoral electroporation of plasmid IL-12 in advanced melanoma

American Association for Cancer Research Annual Meeting 2016

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In vivoIntratumoral Electroporation of Gp96-Ig/Fc-OX40L Stimulates CD8+ T cell Cross Priming to Tumor-Specific Neoantigens

American Association for Cancer Research Annual Meeting 2016

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Intratumoral Delivery of Interleukin-12 DNA via In Vivo Electroporation Leads to Regression of Injected and Non-Injected Tumors in Merkel Cell Carcinoma

2015 European Cancer Congress

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Development of a Catheter-Based Applicator for Immuno-Oncology

First World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies

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Advances in Clinical Electroporation: Tissue Sensing, Feedback Control, and Catheter Technology

First World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies

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Immune Correlates of Intratumoral IL-12 Electroporation

European Society for Medical Oncology 2014 Annual Meeting

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Systemic Anti-Tumor Effect and Clinical Response in a Phase 2 Trial of Intratumoral Electroporation of Plasmid Interleukin-12 in Patients with Advanced Melanoma

American Society of Clinical Oncology 2014 Annual Meeting

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Intratumoral electroporation of plasmid interleukin-12: efficacy and biomarker analyses from a phase 2 study in melanoma (OMS-I100)

Melanoma Bridge Meeting 2014

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